D-serine is a representative D-form amino acid and has crucial roles in mammals, but its role in non-mammals is unclear. Researchers from Japan recently uncovered a functional role of D-serine in a ...

With a newly developed method that compares AI-generated protein sequences with naturally occurring ones, function- and structure-regulating amino acids can be determined much more precisely than ...

Alongside the classical 20 protein amino acids, which are used to build proteins, there are more than 1000 non-protein amino acids in nature. Occasional mistakes can mean these non-protein amino acids ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...