Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

The 8-Bromo-cAMP sodium salt PKA activator, a synthetic analog of cAMP, is one of the most potent tools of investigating and playing with this pathway, which has become an essential part of ...

Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

Gastric cancer cells can activate KRAS-driven signals, enabling autonomous tumor growth by producing their own WNT proteins. New research reveals how gastric cancer cells exploit WNT signaling for ...

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by ...

The field of sepsis research has advanced significantly in recent years, particularly regarding the interplay between immune responses and multiple forms of ...

Scientists have uncovered a gut-specific epigenetic aging mechanism that links inflammation and iron imbalance to cancer risk ...

Glycine, a non-essential amino acid derived from serine, plays an increasingly recognized role in metabolic regulation.

Differences in kinetics of retinal output signals originate at least in part from differences in synaptic output from distinct bipolar cell types.

Hair loss and graying, the earliest visible hallmarks of skin aging, result from the functional decline of hair follicle stem ...