Chronic illnesses such as cancer and autoimmune disorders significantly strain both patients and healthcare systems. Traditional long-term drug therapies, which often have non-specific effects, can ...

As CRISPR and other gene editing therapies move into clinical trials, an important question remains—are these potentially life-saving treatments safe? Genome editing therapies hold great promise for ...

As people grow older, their immune systems do not simply slow down, they often become locked into a simmering, ...

Sickle cell disease (SCD) is a group of blood disorders, including sickle cell anaemia, that is caused by stem blood cells producing mutated red blood cells. This leads to health complications, as the ...

Jason Mast is a general assignment reporter at STAT focused on the science behind new medicines and the systems and people that decide whether that science ever reaches patients. You can reach Jason ...

At age 45, Dr. Lakiea Bailey said, for the longest time, that she was the oldest person with sickle cell anemia that she knew. The executive director of the nonprofit patient advocacy group the Sickle ...

A team of interdisciplinary researchers has developed techniques to improve the efficiency of CRISPR-Cas9, the genome editing technique that earned the Nobel Prize in 2020. A Penn State-led team of ...

An experimental gene editing cell therapy for sickle cell disease has shown encouraging early results in a phase 1/phase 2 multicenter clinical trial, according to researchers at Cleveland Clinic ...

Beam Therapeutics’ experimental gene-editing therapy for sickle cell disease now has its first cut of patient data showing signs of treating the rare blood disorder in a way that could differentiate ...