Researchers from Tokyo Medical and Dental University (TMDU) and Ionis Pharmaceuticals, USA, report a modification wherein replacing the RNA strand of a heteroduplex oligonucleotide with DNA may ...
Adeno-associated virus (AAV) mediates gene targeting in humans by providing exogenous DNA for allelic replacement through homologous recombination. In comparison to other methods of DNA delivery or ...
DNA/DNA double-stranded oligonucleotide is a new concept of oligonucleotide consisting of DNA-based antisense oligonucleotide and DNA-based complementary strand. When α-tocopherol is bound to ...