Enzymes that cut DNA at specific sites are called endonucleases; these enzymes play many roles in genomic replication, fidelity, and defense. The initial discovery of restriction endonucleases in the ...

Calorie restriction (CR) improves health, reduces cancer incidence and extends lifespan in multiple organisms including mice. CR was shown to enhance base excision repair and nucleotide excision ...

In a recent letter published in Nature Aging, researchers assessed the impact of caloric restriction (CR) on biological aging among the comprehensive assessment of the long-term effects of reducing ...

Decades of research has shown that limits on calorie intake by flies, worms, and mice can enhance life span in laboratory conditions. But whether such calorie restriction can do the same for humans ...

Caloric restriction is a dietary intervention that is considered to be a reduction in the total energy intake with the maintenance of proper nutrition. It is associated with several health effects, ...