Researchers have found a new common thread linking nearly all of the trinucleotide repeat expansion diseases, which include ALS, Huntington's Disease and Fragile X Syndrome, involving the complicated ...

Repeat proteins, defined by sequential arrays of short structural motifs, offer an intriguing departure from the folding behaviour of conventional globular proteins. Their modular architecture enables ...

The unusual folding pattern of PGK was first observed experimentally over 25 years ago. Whereas most proteins fit the "two-state" model of exponential folding kinetics, the molecules of PGK followed a ...

image: Researchers at the University of Pennsylvania have found a new common thread linking nearly all of the trinucleotide repeat expansion diseases, which include ALS, Huntington's Disease and ...