The genetic code, a universal blueprint for life, governs how DNA and RNA sequences translate into proteins. While its complexity has inspired generations of scientists, its origins remain a topic of ...

This image illustrates the chemical structures of the five main nucleobases found in DNA and RNA. The pyrimidines, thymine (DNA), uracil (RNA), and cytosine are shown on top while the purines, adenine ...

For decades, the central dogma of molecular biology—DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease. This model explained ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...

Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases. (Image: Wikimedia Commons, CC SA 3.0) The most common type of base pairing is the Watson-Crick base ...

DNA sequencing is one of today's most critical scientific fields, powering leaps in humanity's understanding of genetic causes of cancer, neurodegenerative diseases, and diabetes. One issue facing the ...

The expression of genes has to be very carefully controlled by cells; serious problems can arise when genes are expressed in the wrong places, at the wrong times, or at the wrong levels, for some ...

Genetic counseling (GC) in the era of next generation sequencing (NGS) to diagnose microsatellite instability (MSI) and deficient mismatch repair (dMMR) expression in colorectal cancer (CRC). This is ...