COOH) represents the protonated form of the organic acid, whereas lactate (CH₃CH (OH)COO⁻) represents its conjugated base.

Lactate is the end product of the cytosolic metabolism of glucose, and its accumulation in the blood signals an increase in production or a decrease in utilization, or both. The liver is a major site ...

A new initiative by The Society for Cardiovascular Angiography & Interventions (SCAI) proposes a new framework and call to action for managing cardiogenic shock (CS), establishing lactate clearance ...

The International Brain pH Project Consortium unveils groundbreaking findings in a large-scale animal model study, indicating altered brain pH and lactate levels as a transdiagnostic endophenotype in ...

A volunteer is monitored after being given a large dose of glucose to determine how well people switch from fat to carbohydrate metabolism as they age. In the tests at UC Berkeley, subjects had their ...

The Warburg effect describes how cancer cells switch from oxidative phosphorylation to glycolysis even in oxygen-rich conditions, producing massive amounts of lactate that accumulate in the tumor ...

A recent Nature Metabolism study reports that circulating lactate levels are positively associated with weight loss in cancer cachexia patients. Mouse model experiments also revealed that ...

As our bodies perform strenuous exercise, we begin to breathe faster as we attempt to shuttle more oxygen to our working muscles. The body prefers to generate most of its energy using aerobic methods, ...