Nature

Transformation of severe congenital neutropenia to early acute lymphoblastic leukemia in a patient with HAX1 mutation and without G-CSF administration or receptor mutation

The diagnosis of severe congenital neutropenia (SCN) is clinically based on profound persistent neutropenia (absolute neutrophil count (ANC). We previously reported on an SCN patient who transformed ...
JSTOR Daily

Tissue-Specific Transformation by Epidermal Growth Factor Receptor: A Single Point Mutation within the ATP-Binding Pocket of the erbB Product Increases its Intrinsic Kinase ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, No. 23 (Dec., 1990), pp. 9103-9107 (5 pages) Avian c-erbB is activated to a leukemia oncogene following ...
ascopubs.org

Novel ETV1 mutation in small cell lung cancer transformation resistant to EGFR tyrosine kinase inhibitors.

Role of chest radiation in extensive-stage small cell lung cancer with ipsilateral pleural effusion. This is an ASCO Meeting Abstract from the 2021 ASCO Annual Meeting I. This abstract does not ...
Live Science

New study provides first evidence of non-random mutations in DNA

This goes against one of the key assumptions of the theory of evolution. When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works. Genetic changes that ...