Proteolytic degradation products of fibrinogen, produced as a result of excessive fibrinolysis, have been demonstrated in the blood of cirrhotic patients. 7,8 Such degradation products, when formed in ...

The first study to examine the effects of whole-chocolate consumption on ex vivo platelet function has shown that dark chocolate acutely reduces collagen-stimulated platelet aggregation and reduces ...

Hyperglycaemia is associated with increased platelet aggregation that increases the risk of thrombosis in people with type-2 diabetes and cardiovascular disease. Low glycemic index (GI) meals high in ...

Figure 1: Targeted disruption of P2y1 locus and aggregation responses of wild-type (WT) and P2y1 –/– platelets. Figure 2: Cellular events in stimulated P2y1 –/– and wild-type platelets. Figure 3: ...

A major factor in coronavirus disease 2019 (COVID-19)-associated mortality is the development of coagulation abnormalities that may result in thromboembolism. Human platelets have been found by ...

Researchers have identified serine threonine kinase 10 as a key regulator of platelet function, haemostasis and ...

Scientists have provided new details about how cancer cells spread by surrounding themselves with platelets -- the blood cells needed for blood clotting. These results could help design new drugs that ...

When cancer cells and platelets mix, the risk of metastasis and cancer-related deep vein thrombosis (DVT) and pulmonary embolism (PE) increases, but a small, proof-of-concept study suggests that the ...

Diminished platelet autophagy potentially contributes to thrombocytopenia in cirrhotic patients. H 2 S modulates platelet autophagy and functions possibly via the PDGFR-α/PI3K/Akt/mTOR signaling ...

Vegetarians, vegans, and omnivores given an oral choline supplement for 2 months have a more than tenfold increase in trimethylamine N-oxide (TMAO), a metabolite derived from the gut microbiota that ...

In a recent study published in the IUBMB journal, researchers assessed the association between platelet-activating factor (PAF) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike ...