The New England Journal of Medicine

A Randomized Trial of Acute Normovolemic Hemodilution in Cardiac Surgery

Patients undergoing cardiac surgery often receive red-cell transfusions, along with the associated risks and costs. Early intraoperative normovolemic hemodilution (i.e., acute normovolemic ...
ascopubs.org

A multicenter, randomized, controlled, open-label trial to determine the optimal duration of steroid therapy for mild pneumonitis associated with immune checkpoint inhibitors.

Results of a multisite randomized trial of Bright IDEAS-Young Adults: Efficacy of problem-solving skills training on distress and health-related quality of life. This is an ASCO Meeting Abstract from ...
The New England Journal of Medicine

Randomized Trial of Targeted Indoor Spraying to Prevent Aedes-Borne Diseases

Targeted indoor residual spraying focuses insecticide applications on common resting surfaces of Aedes aegypti mosquitoes (an arboviral disease vector) in houses, such as exposed lower sections of ...
Opinion
Edzard ErnstOpinion

The credebility of trials of spinal manipulative therapy is questionable

Reliable reporting and publication practices are essential for trustworthy evidence synthesis and clinical decision-making. This analysis aimed to identify latent classes of randomized controlled ...
Heart

Use and misuse of composite endpoints in randomised clinical trials

Composite endpoints are widely used in large randomised cardiovascular outcome trials. They are frequently referred to as ...
ascopubs.org

An international, multicenter, prospective randomized trial of adjuvant chemotherapy for stage Ia-IIa non-small cell lung cancer identified as high-risk by a 14-gene molecular ...

Perioperative nivolumab (NIVO) vs placebo (PBO) in patients (pts) with resectable NSCLC: Updated survival and biomarker analyses from CheckMate 77T. This is an ASCO Meeting Abstract from the 2025 ASCO ...