cirm.ca.gov

Clinical Study of T stem cell memory (Tscm)-based CAR-T cells in Patients with Multiple Myeloma

Translational Candidate s15.BsAb.BCMA-CAR NK cells derived from CD34(+) umbilical cord blood hematopoietic stem cells Area of Impact patients with multiple myeloma ...
cirm.ca.gov

Cardiac Development at a Single-Cell Resolution.

Mammalian heart development is a complex process. Recent advances in using stem-cell-derived cardiac progenitor cells along with advanced genetic methods are described that will lead to a better ...
cirm.ca.gov

The cardiac conduction system: History, development, and disease.

The system in the heart that controls muscle contraction is discussed. Known diseases relating to the development of heart contraction and clinical approaches to correct defects in heart contraction ...
cirm.ca.gov

CRISPR activation for SCN2A-related neurodevelopmental disorders.

Serena Tamura, Andrew D Nelson, Perry W E Spratt, Elizabeth C Hamada, Xujia Zhou, Henry Kyoung, Zizheng Li, Coline Arnould, Vladyslav Barskyi, Beniamin Krupkin, Kiana Young, Jingjing Zhao, Stephanie S ...
cirm.ca.gov

Deep learning the dynamic regulatory sequence code of cardiac organoid differentiation.

Eyal Metzl-Raz, Ryan Zhao, Salil Deshpande, Jackson Powell, Elizabeth G Porter, Yassine Zouaghi, Betty B Liu, Samuel H Kim, Immanuel Abdi, Ivy Evergreen, Megha Agarwal, Maya U Sheth, Joshua Rico, ...
cirm.ca.gov

A human-specific regulatory mechanism revealed in a pre-implantation model.

Pre-implantation events in human development are difficult to study due to ethical concerns. This work utilizes a human stem-cell-based blasted model to test the genetic regulation of implantation ...
cirm.ca.gov

California’s Stem Cell Agency Invests in Stem Cell-Based Therapies Targeting Sickle Cell Disease and Cancer

February 22, 2018 – Oakland, CA The California Institute for Regenerative Medicine (CIRM), California’s Stem Cell Agency, today invested almost $10 million in stem cell research targeting sickle cell ...
cirm.ca.gov

CIRM Awards Nearly $100 Million to Boost Discovery, Translational, and Clinical Disease Research

South San Francisco, CA, January 30, 2025 – The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutions dedicated to regenerative medicine, has awarded nearly ...
cirm.ca.gov

CIRM Announces Leadership Transition

South San Francisco, CA, Nov. 7, 2023– The California Institute for Regenerative Medicine (CIRM), the world’s largest institution dedicated to regenerative medicine, announced today that Maria T.
cirm.ca.gov

CIRM approves $8 million award for plasma cell disorder therapy, $27 million to boost collaboration among California researchers

South San Francisco, CA, July 25, 2024 – The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutions dedicated to regenerative medicine, awarded nearly $35 ...
cirm.ca.gov

CIRM Announces Recommendations from Strategic Allocation Framework

South San Francisco, CA, September 27, 2024 – The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutes dedicated to regenerative medicine, announced key ...
cirm.ca.gov

CIRM awards $4.7 million for vision loss gene therapy

South San Francisco, CA, May 29, 2025 – The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutions dedicated to regenerative medicine, awarded $4.7 million to ...