A research team has developed DeepCodon, a deep learning–based codon optimization tool that significantly improves heterologous protein expression in Escherichia coli while preserving functionally ...

Bayer has filed separate lawsuits against the creators of three COVID-19 vaccines, claiming they violated intellectual ...

Sherry Gu, Executive Vice President and CTO at WuXi Biologics, explains the critical challenges of developing bispecific ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...

While codons (combinations of three nucleotides) may vary in which do what functions, a long-standing rule was that each codon serves one specific purpose. New evidence, however suggests that ...

Researchers are adding new evidence to the emerging concept that 'silent' or synonymous mutations may have crucial consequences. Their study showed how a synonymous mutation in one gene can ...

Living organisms synthesize a staggering variety of proteins by combining 20 amino acids into chains of any length and order. In the past, to expand protein diversity beyond the scope of these 20 ...