Comprehensive map reveals how E3 ligases organize protein cleanup in human cells

Individual mammalian cells contain billions of protein molecules, which must be synthesized, deployed, and removed with ...
CNET

Better Than a Ball Machine: I Checked Out 2 Tennis Robots and Now Want One

My first robot stop was Acemate's booth, where it had its tennis robot rolling back and forth on a mini tennis court opposite ...
Interesting Engineering

AI meets DNA: US scientists design massive genetic circuit libraries faster than ever

New CLASSIC technique uses AI and massive DNA libraries to predict genetic circuit performance faster and more accurately.
eLife

Separating selection from mutation in antibody language models

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...
eLife

Retrosplenial cortex enables context-dependent goal-directed sensorimotor transformation

This important study combines optogenetic manipulations and wide-field imaging to show that the retrosplenial cortex controls behavioral responses to whisker deflection in a context-dependent manner.
BGR

The Steam Machine Is Going To Cost More Than You Think, And It's Pretty Clear Why

Steam is a popular computer gaming platform, and now, it has rocked the industry with the announcement of its TV-compatible console, the Steam Machine. It promises enough power to play an internal ...
Polygon

Steam Machine is the only way I want to play PC games from now on

For most of my life, I've been a console gamer. From the moment I got a Nintendo Entertainment System (NES) as a combination birthday and Christmas present at the tail end of 1986, I became absolutely ...
IGN

Don't Expect the Steam Machine Price to Follow a 'Console Pricing Model' of $500

Valve’s announcement of the Steam Machine has sparked much debate online about the company’s return to the PC in the living room space, but one key piece of information remains unknown: price. The ...
GameSpot

Steam Machine Release Date Window, Price Speculation, And Everything We Know About Valve's Next-Gen Living Room PC

More than 12 years ago, Steam creator Valve attempted to usurp Microsoft's hold on PC gaming by introducing the first Steam Machine. The reliance on Linux and a loose hold on OEM hardware ...
Game Rant

What Is a GabeCube, and Why the Steam Machine Has Become Meme Gold

LB Beistad is a writer and musician based in Nashville, TN. Her love of gaming began with her cousin introducing her to Banjo Kazooie and Jak and Daxter. It was love at first play. Since then, she has ...
Nerdbot

Hire Python Programmers for Machine Learning and AI Success

If there is one skill that sits at the heart of most successful AI and machine learning projects today, it is Python. Whether a company wants to build smarter automation, design predictive solutions, ...
TweakTown

Valve's Steam Machine is upgradable, but not where it's wanted most

TL;DR: Valve's upcoming Steam Machine is a compact gaming PC featuring an AMD RDNA 3 GPU with 8GB GDDR6 VRAM, designed for 4K 60FPS gaming using FSR 3 upscaling. Users can upgrade RAM and SSD storage, ...