CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the double ...
Base editors enable nucleotide conversions but have fixed editing patterns. Here, authors develop Plug-in Base Editor, a modular system programming deaminase positioning via epitope-antibody ...
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