In this study, we employed unbiased lipidomic and transcriptomic approaches to investigate the contribution of IRE1α signalling to lipid metabolism in TNBC. This system biology framework enables the ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. One way cells control the speed and ...
Background: Reactive oxygen species (ROS) function as signaling molecules to regulate reparative macrophage polarization essential for ischemia-induced neovascularization and regeneration of skeletal ...
Epidural fibrosis (EF), associated with various biological factors, is still a major troublesome clinical problem after laminectomy. In the present study, we initially demonstrate that sensory nerves ...
Intracerebral Hemorrhage (ICH) is a destructive neurovascular disease with no efficient treatment. Trapped Red Blood Cells (RBCs) in the brain lyse releasing toxic heme from hemoglobin. Heme, a ...
A recent publication in Cell demonstrates that arginine, an amino acid that facilitates various cellular processes, including cellular growth, also promotes tumor growth. The study shows that arginine ...
Signaling rewiring allows tumors survive therapy. Here we show that the decrease of the master regulator microphthalmia transcription factor (MITF) in lethal prostate cancer (PCa) unleashes eukaryotic ...
In the hunt for new antibiotics, people have looked in myriad locations. At the University of Pennsylvania, Cesar de la Fuente’s team goes hunting in the protein world. The researchers aim to find ...
Artificial Intelligence is all over the news now, leading to reactions ranging from favour (it will drive efficiency and save effort) to fury (robots/software will steal our jobs) to fatuous (the ...
About 430 million people around the world experience disabling hearing loss. In the United States, approximately 37.5 million adults report some trouble hearing. Hearing loss can happen when any part ...
Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, United States Graduate Program in Pharmaceutical Science, ...
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