A new 'crystalline sponge' for drug discovery: APF-80 illuminates materials design

Many natural compounds that act on the human body provide active ingredients for medicines or clues for developing them, and ...

Comprehensive map reveals how E3 ligases organize protein cleanup in human cells

Individual mammalian cells contain billions of protein molecules, which must be synthesized, deployed, and removed with ...
IEEE

PGDTA: Predicting Drug-Target Affinity Using Three-Dimensional Structure of Protein Pocket and Graph Neural Network

Abstract: Drug-Target Affinity (DTA) prediction plays a crucial role in drug discovery, and accurate DTA prediction can significantly reduce the cost of drug development. While most studies focus on ...
IEEE

Real-Time Shape Estimation of Tensegrity Structures Using Strut Inclination Angles

Abstract: Tensegrity structures are becoming widely used in robotics, such as continuously bending soft manipulators and mobile robots to explore unknown and uneven environments dynamically.