Comprehensive map reveals how E3 ligases organize protein cleanup in human cells

Individual mammalian cells contain billions of protein molecules, which must be synthesized, deployed, and removed with ...
IEEE

High-Dimensional Hyperparameter Optimization via Adjoint Differentiation

Abstract: As an emerging machine learning task, high-dimensional hyperparameter optimization (HO) aims at enhancing traditional deep learning models by simultaneously optimizing the neural networks’ ...
IEEE

Group-Specific SVM With Bilevel Programming Methods for Parameter Optimization and Explainable AI in Urban Quality of Life Prediction

Abstract: The assessment of urban quality of life (UQoL) is a multidimensional challenge involving socioeconomic, environmental, and infrastructure-related variables that, due to changes in the ...
Variety

‘The Smashing Machine’ Sets HBO Max Release Date

Audiences will get a second chance to see Dwayne Johnson‘s most dramatic transformation of his career when “The Smashing Machine” lands on HBO Max on Jan. 23. Helmed by Benny Safdie, “The Smashing ...