Dr Anna Wilkins’ group is investigating how to target the tumour microenvironment of bladder and prostate cancer to prevent treatment resistance, especially to radiation given with curative intent.
Age-related intervertebral disc (IVD) pathologies are a major driver of chronic low back pain and disability. Long framed as ...
Genomic and Multi-Omics Insights into Carcinogenesis Induced by Environmental and Chemical Exposures
Environmental and chemical exposures have emerged as critical contributors to the global cancer burden. Sources such as dietary contaminants, food ...
Abstract: Spatial transcriptomics is an emerging technology that allows for analysis of cellular and molecular heterogeneity at spatial resolution. The accurate identification of pathological regions ...
Spatially resolved transcriptomics (SRT) simultaneously captures spatial coordinates, pathological features, and transcriptional profiles of cells within intact tissues, offering unprecedented ...
Abstract: Spatial transcriptomics (ST) is a novel technique that simultaneously captures pathological images and gene expression profiling with spatial coordinates. Since ST is closely related to ...
The preprint is available here. DeepSpot2Cell predicts virtual single-cell spatial transcriptomics as follows: (1) During training, the model takes as input (i) the cropped cell tile defined by the ...
Background Intraductal papillary mucinous neoplasms (IPMNs) are precursor lesions of pancreatic cancer with highly variable malignant potential. Current understanding of their biology remains ...
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